Objective: To study the perioperative nursing measures and nursing effect of arterial embolization in the treatment of uterine fibroids.Methods: 2021.1-12,122 patients with surgical pulse embolization were divided into management group (full intervention perioperative care) and reference group (general perioperative care) to compare the nursing effect.Results: Compared with the reference group, lower complications, better physical comfort and emotional status, higher medical service satisfaction, and lower care complaints rate were found in the management group, (P <0.05).Conclusion: The perioperative treatment of uterine fibroids artery embolism can effectively reduce the risk of postoperative complications, improve patient comfort, and promote it.